Metabolic Syndrome Status Changes and Cognitive Functioning: Insights from the Lifelines Cohort Study
Background: Metabolic syndrome is associated with increased risk of dementia. Yet, findings on how longitudinal development of metabolic syndrome status affects cognition remain controversial. Objectives: This study examines whether individuals with different changes in metabolic syndrome […]
Engagement in online cognitive testing with the Cogstate brief battery among a multinational cohort of people with focal epilepsy
Objective: The Human Epilepsy Project (HEP) is a large multinational cohort study of people with newly diagnosed and treated focal epilepsy. HEP utilized the Cogstate Brief Battery (CBB) as a self-directed online assessment to examine cognitive […]
Gaba-producing lactobacilli boost cognitive reactivity to negative mood without improving cognitive performance: A human Double-Blind Placebo-Controlled Cross-Over study
Background: Psychobiotic bacteria are probiotics able to influence stress-related behavior, sleep, and cognitive outcomes. Several in vitro and human studies were performed to assess their physiological potential, to find strains having psychotropic activity in humans, and […]
Cognitive performance and mortality among patients receiving autologous hematopoietic stem cell transplant
Objectives: Patients undergoing autologous hematopoietic stem cell transplant (HCT) are at risk for death and remain understudied relative to those undergoing allogeneic HCT. Cognitive functioning may be a useful indicator of mortality risk. We examined cognition […]
Association of Basal Forebrain Atrophy With Cognitive Decline in Early Alzheimer Disease
Background and Objectives In early Alzheimer disease (AD), β-amyloid (Aβ) deposition is associated with volume loss in the basal forebrain (BF) and cognitive decline. However, the extent to which Aβ-related BF atrophy manifests as cognitive decline […]