Publications

Access hundreds of peer-reviewed papers published by neuroscientists using Cogstate technology.

Adaptive behavior in autism: Minimal clinically important differences on the Vineland‐II

Authors: C H Chatham, K I Taylor, T Charman, X Liogier D'ardhuy, E Eule, A Fedele, A Y Hardan, E Loth, L Murtagh, M Del Valle Rubido, A San Jose Caceres, J Sevigny, L Sikich, L Snyder, J E Tillmann, P E Ventola, K L Walton-Bowen, P P Wang, T Willgoss, F Bolognani

Journal: Autism Research

Year Published: 2018

Abstract: Autism Spectrum Disorder (ASD) is associated with persistent impairments in adaptive abilities across multiple domains. These social, personal, and communicative impairments become increasingly pronounced with development, and are present regardless of IQ. The Vineland Adaptive […]

BrainGNN: Interpretable Brain Graph Neural Network for fMRI Analysis

Authors: Xiaoxiao Li, Yuan Zhou, Nicha Dvornek, Muhan Zhang, Siyuan Gao, Juntang Zhuang, Dustin Scheinost, Lawrence H Staib, Pamela Ventola, James S Duncan

Journal: Medical Image Analysis

Year Published: 2021

Understanding which brain regions are related to a specific neurological disorder or cognitive stimuli has been an important area of neuroimaging research. We propose BrainGNN, a graph neural network (GNN) framework to analyze functional magnetic resonance […]

Gaboxadol in Fragile X Syndrome: A 12-Week Randomized, Double-Blind, Parallel-Group, Phase 2a Study

Authors: Dejan B Budimirovic, Kelli C Dominick, Lidia V Gabis, Maxwell Adams, Mathews Adera, Linda Huang, Pamela Ventola, Nicole R Tartaglia, Elizabeth Berry-Kravis

Journal: Frontiers in Pharmacology

Year Published: 2021

Background: Fragile X syndrome (FXS), the most common single-gene cause of intellectual disability and autism spectrum disorder (ASD), is caused by a >200-trinucleotide repeat expansion in the 5′ untranslated region of the fragile X mental retardation […]

CD19/22 CAR T-cells in Children and Young Adults with B-ALL: Phase I Results and Development of a Novel Bicistronic CAR

Authors: Haneen Shalabi, Haiying Qin, Angela Su, Bonnie Yates, Pamela L. Wolters, Seth M Steinberg, John A Ligon, Sara Silbert, Kniya DéDé, Mehdi Benzaoui, Sophia Yael Goldberg, Sooraj Achar, Dina Schneider, Shilpa A Shahani, Lauren Little, Toni Foley, John C Molina, Sandhya Panch, Crystal L. Mackall, Daniel W. Lee, Christopher D Chien, Marie Pouzolles, Mark A Ahlman, Constance M Yuan, Hao-Wei Wang, Yanyu Wang, Jon Inglefield, Mary Anne Tamula, Staci Martin, Steven L Highfill, Gregoire Altan-Bonnet, David F Stroncek, Terry J Fry, Naomi Taylor, Nirali N Shah

Journal: Blood

Year Published: 2022

Remission durability following single-antigen targeted chimeric antigen receptor (CAR) T-cells is limited by antigen modulation, which may be overcome with combinatorial targeting. Building upon our experiences targeting CD19 and CD22 in B-cell acute lymphoblastic leukemia (B-ALL), […]

Efficacy and Safety of Lurasidone in Adolescents with Schizophrenia: A 6-Week, Randomized Placebo-Controlled Study

Authors: Robert Goldman, Antony Loebel, Josephine Cucchiaro, Ling Deng, Robert L Findling

Journal: Journal of Child and Adolescent Psychopharmacology

Year Published: 2017

Objective: To evaluate the efficacy and safety of lurasidone in acutely symptomatic adolescent patients with schizophrenia. Methods: Patients aged 13-17 years were randomly assigned to 6 weeks of double-blind, fixed-dose lurasidone (40 or 80 mg/day) or […]

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