Publications
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Ultra-processed food intake, cognitive function, and dementia risk: A cross-sectional study of middle-aged and older Australian adults
Introduction: Ultra-processed food (UPF) consumption is linked to over 30 adverse health outcomes, including several risk factors for dementia such as cardiovascular disease, type 2 diabetes, and obesity. We aimed to examine the association of UPF […]
Memantine for Prevention of Cognitive Late Effects in Children and Adolescents Receiving Radiotherapy for Brain Tumors: A Randomized, Controlled, Pilot Trial
Background: Children receiving irradiation for brain tumors are at significant risk for cognitive deficits that notably impact quality of life. This is the first randomized, controlled, investigation of the feasibility, acceptability, and preliminary efficacy of memantine […]
Association of serum biomarkers for lipid and amino acid metabolism with cognition in adolescents
Background: We investigated the associations of serum biomarkers for lipid and amino acid metabolism with cognition in adolescents. Methods: Altogether 276 adolescents aged 15-16 years were studied. Serum biomarkers for lipid and amino acid metabolism were […]
Trajectory of Neurocognitive Functioning in Children Treated for Acute Lymphoblastic Leukemia (ALL): Dana-Farber Cancer Institute ALL Consortium Study 16-001
Background: Children treated for acute lymphoblastic leukemia (ALL) are at risk of neurocognitive deficits in attention-concentration, working memory, executive function, and psychomotor speed. Objectives: This study evaluated longitudinal trajectories and medical/demographic associations with neurocognitive outcomes during […]
Evaluating Physical Frailty as a Marker of Cognitive Health in Older Adults without Dementia
Physical frailty is associated with adverse health outcomes in older adults, including cognitive decline; however, the underlying biological and pathophysiological mechanisms linking frailty to neuropathological biomarkers remain underexplored, particularly in older adults without dementia. This study […]