Computerized Cognitive Testing for Use in Clinical Trials: A Comparison of the NIH Toolbox and Cogstate C3 Batteries
Background: As prevention trials for Alzheimer’s disease move into asymptomatic populations, identifying older individuals who manifest the earliest cognitive signs of Alzheimer’s disease is critical. Computerized cognitive testing has the potential to replace current gold standard […]
Vortioxetine for major depressive disorder, vasomotor, and cognitive symptoms associated with the menopausal transition
Background: In a preliminary trial, we assessed the efficacy of vortioxetine for major depressive disorder (MDD) during the menopausal transition. Secondary outcomes included hot flashes (HFs), anxiety, and cognitive complaints. Methods: Perimenopausal and early postmenopausal women […]
Sensitivity of the Cogstate Test Battery for Detecting Prolonged Cognitive Alterations Stemming From Sport-Related Concussions
Objective: To determine if the Cogstate test battery contains the requisite sensitivity to detect prolonged cognitive alterations. Methods: One hundred twenty collegiate athletes (71 with a history of concussion; 49 controls) completed the Cogstate test battery, […]
No Seasonal Changes in Cognitive Functioning Among High School Football Athletes: Implementation of a Novel Electrophysiological Measure and Standard Clinical Measures
Objective: To evaluate neuroelectric and cognitive function relative to a season of football participation. Cognitive and neuroelectric function declines are hypothesized to be present in football athletes. Design: Observational. Setting: Athletic fields and research laboratory. Patients […]
The Effects of the Removal of Electronic Devices for 48 hours on Sleep in Elite Judo Athletes
Objective: This study examined the effects of the removal of electronic devices (i.e., smartphones, etc.) for 48 hours on sleep quality and next-day athletic and cognitive performance in elite Judo athletes. Participants: Over 6 days and […]