Impaired visual, working, and verbal memory in first-episode, drug-naive patients with major depressive disorder in a Chinese population
Cognitive impairment has been observed in patients with major depressive disorder (MDD). However, it remains unclear whether the deficits in specific cognitive domains are present in first-episode, drug-naïve patients or medicated patients. In the present study, […]
Effect of Chlorogenic Acid Intake on Cognitive Function in the Elderly: A Pilot Study
Objective: To evaluate the effect of chlorogenic acids (CGAs) intake on cognitive function. Methods: In this pilot study, the Cogstate and CNS Vital Signs test batteries were used to evaluate cognitive function in 8 healthy elderly […]
Computerized Cognitive Testing for Use in Clinical Trials: A Comparison of the NIH Toolbox and Cogstate C3 Batteries
Background: As prevention trials for Alzheimer’s disease move into asymptomatic populations, identifying older individuals who manifest the earliest cognitive signs of Alzheimer’s disease is critical. Computerized cognitive testing has the potential to replace current gold standard […]
Vortioxetine for major depressive disorder, vasomotor, and cognitive symptoms associated with the menopausal transition
Background: In a preliminary trial, we assessed the efficacy of vortioxetine for major depressive disorder (MDD) during the menopausal transition. Secondary outcomes included hot flashes (HFs), anxiety, and cognitive complaints. Methods: Perimenopausal and early postmenopausal women […]
Sensitivity of the Cogstate Test Battery for Detecting Prolonged Cognitive Alterations Stemming From Sport-Related Concussions
Objective: To determine if the Cogstate test battery contains the requisite sensitivity to detect prolonged cognitive alterations. Methods: One hundred twenty collegiate athletes (71 with a history of concussion; 49 controls) completed the Cogstate test battery, […]
