alzheimer's disease

Building clinically relevant outcomes across the Alzheimer’s disease spectrum

Authors: Dorene M. Rentz, Alette M. Wessels, Ananth V. Annapragada, Anna‐Karin Berger, Chris J. Edgar, Michael Gold, David S. Miller, Christopher Randolph, J. Michael Ryan, Glen Wunderlich, Megan Canniere Zoschg, Dominic Trépel, David S. Knopman, Adam M. Staffaroni, Lisa J. Bain, Maria C. Carrillo, Christopher J. Weber

Journal: Alzheimer's & Dementia

Year Published: 2021

Demonstrating that treatments are clinically meaningful across the Alzheimer’s disease (AD) continuum is critical for meeting our goals of accelerating a cure by 2025. While this topic has been a focus of several Alzheimer’s Association Research […]

Brain health registry GenePool study: A novel approach to online genetics research

Authors: Juliet Fockler, Winnie Kwang, Miriam T Ashford, Derek Flenniken, Joshua Hwang, Diana Truran, R Scott Mackin, Chengshi Jin, Ruth O'Hara, Joachim F Hallmayer, Jerome A Yesavage, Michael W Weiner, Rachel L Nosheny

Journal: Alzheimer's & Dementia

Year Published: 2021

Introduction Remote data collection, including the establishment of online registries, is a novel approach to efficiently identify risk for cognitive decline and Alzheimer’s disease (AD) in older adults, with growing evidence for feasibility and validity. Addition […]

Online study partner-reported cognitive decline in the Brain Health Registry

Authors: Rachel L. Nosheny, Monica R. Camacho, Philip S. Insel, Derek Flenniken, Juliet Fockler, Diana Truran, Shannon Finley, Aaron Ulbricht, Paul Maruff, Kristine Yaffe, R. Scott Mackin, Michael W. Weiner, Alzheimer's Disease Neuroimaging Initiative

Journal: Alzheimer's & Dementia

Year Published: 2018

Introduction Methods for efficiently identifying cognitive decline and Alzheimer’s disease (AD) are a critical unmet need. The goal of this work was to validate novel online study partner (SP)-reported outcomes to identify cognitive decline in older […]

Patient perspectives of the experience of a computerized cognitive assessment in a clinical setting

Authors: Julie M Robillard, Jen-Ai Lai, Julia M Wu, Tanya L Feng, Sherri Hayden

Journal: Alzheimer's & Dementia

Year Published: 2018

Introduction Computerized assessments are becoming widely accepted in the clinical setting and as a potential outcome measure in clinical trials. To gain patient perspectives of this experience, the aim of the present study was to investigate […]

The Brain Health Registry: An internet-based platform for recruitment, assessment, and longitudinal monitoring of participants for neuroscience studies

Authors: Michael W. Weiner, Rachel Nosheny, Monica Camacho, Diana Truran-Sacrey, R. Scott Mackin, Derek Flenniken, Aaron Ulbricht, Philip Insel, Shannon Finley, Juliet Fockler, Dallas Veitcha

Journal: Alzheimer's & Dementia

Year Published: 2018

Introduction Recruitment, assessment, and longitudinal monitoring of participants for neuroscience studies and clinical trials limit the development of new treatments. Widespread Internet use allows data capture from participants in an unsupervised setting. The Brain Health Registry, […]

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