Cognitive impairment and decline in cognitively normal older adults with high amyloid-β: A meta-analysis.

Authors: Baker JE, Hassenstab J, Lim YY, Maruff P, Masters CL, Pietrzak RH, Snyder PJ

Journal: Alzheimer's & Dementia

INTRODUCTION: This meta-analysis aimed to characterize the nature and magnitude of amyloid (Aβ)-related cognitive impairment and decline in cognitively normal (CN) older individuals. METHOD: MEDLINE Ovid was searched from 2012 to June 2016 for studies reporting […]

The nature and severity of cognitive impairment associated with adjuvant chemotherapy in women with breast cancer: A meta-analysis of the current literature.

Authors: Falleti MG, Maruff P, Phillips KA, Sanfilippo A, Weih L

Journal: Brain and cognition

OBJECTIVE: Several studies have identified that adjuvant chemotherapy for breast cancer is associated with cognitive impairment; however, the magnitude of this impairment is unclear. This study assessed the severity and nature of cognitive impairment associated with […]

The effects of growth hormone (GH) deficiency and GH replacement on cognitive performance in adults: A meta-analysis of the current literature.

Authors: Burman P, Falleti MG, Harris A, Maruff P

Journal: Psychoneuroendocrinology

OBJECTIVE: There is growing evidence in the neuropsychological literature that growth hormone (GH) deficiency is associated with cognitive impairment. There is also evidence that this impairment may be ameliorated with GH replacement therapy. The current study […]

Decreased serum levels of mature brain-derived neurotrophic factor (BDNF), but not its precursor proBDNF, in patients with major depressive disorder.

Authors: Enohara M, Hasegawa T, Hashimoto K, Hashimoto T, Ishikawa M, Iyo M, Kanahara N, Kimura A, Nakazato M, Niitsu T, Shiina A, Shiraishi T, Watanabe H, Yoshida T

Journal: Public Library of Science One

BACKGROUND: Meta-analyses have identified serum levels of brain-derived neurotrophic factor (BDNF) as a potential biomarker for major depressive disorder (MDD). However, at the time, commercially available human ELISA kits are unable to distinguish between proBDNF (precursor […]

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