HIV

Designing and Evaluating Brain Powered Games for Cognitive Training and Rehabilitation in At-Risk African Children

Authors: B Giordani, B Novak, A Sikorskii, P Bangirana, N Nakasujja, B M Winn, M J Boivin

Journal: Global Mental Health

Year Published: 2015

Background: Valid, reliable, accessible, and cost-effective computer-training approaches can be important components in scaling up educational support across resource-poor settings, such as sub-Saharan Africa. The goal of the current study was to develop a computer-based training […]

Cerebral function in perinatally HIV-infected young adults and their HIV-uninfected sibling controls

Authors: Jane Ashby, Caroline Foster, Lucy Garvey, Tania Wan, Joanna Allsop, Yasotharan Paramesparan, Simon D Taylor-Robinson, Sarah Fidler, Alan Winston

Journal: HIV Clinical Trials

Year Published: 2015

Background: Perinatally acquired HIV-infected (PaHIV) young adults undergo neurodevelopment in the presence of HIV infection and antiretroviral therapy, which may lead to neurocognitive (NC) impairment. Knowledge of NC function in this group is sparse and control […]

A pilot study of the neuropsychological benefits of computerized cognitive rehabilitation in Ugandan children with HIV

Authors: Michael J Boivin, Rachelle A Busman, Sujal M Parikh, Paul Bangirana, Connie F Page, Robert O Opoka, Bruno Giordani

Journal: Neuropsychology

Year Published: 2010

Objective: Because antiretroviral treatment (ART) fails to improve neurocognitive impairment in children with HIV, we completed a pilot study evaluating the feasibility and cognitive benefit of computerized cognitive rehabilitation therapy (CCRT) in Ugandan children with HIV. […]

Effect of hyperbilirubinaemia on neurocognitive, renal, bone and cardiovascular markers in HIV infection treated with boosted protease inhibitors

Authors: Tristan J Barber, Graeme Moyle, Andrew Hill, Gurmit Jagjit Singh, Marta Boffito, Mark Nelson

Journal: Journal of the International AIDS Society

Year Published: 2014

Introduction: Use of some protease inhibitors (PI) is associated with unconjugated hyperbilirubinaemia (HBR), due to inhibition of UGT1A1. As observed in Gilbert’s syndrome, HBR may have antioxidant and anti-inflammatory effects. Inflammation may be relevant to neurocognitive […]

Does acute hepatitis C infection affect the central nervous system in HIV-1 infected individuals?

Authors: A Winston, L Garvey, E Scotney, D Yerrakalva, J M Allsop, E C Thomson, V P B Grover, J Main, J I Cox, M Wylezinska, S D Taylor-Robinson

Journal: Journal of Viral Hepatitis

Year Published: 2010

Central nervous system (CNS) manifestations of chronic hepatitis C virus (HCV) and chronic human immune deficiency virus-1 (HIV-1) infections have been reported, but the impact of acute HCV infection on the CNS is unknown. A total […]

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