Cogstate battery

Long-term clinical, imaging and cognitive outcomes association with MS immunopathology

Authors: Alicja Kalinowska-Lyszczarz, Jan-Mendelt Tillema, William Oliver Tobin, Yong Guo, Stephen D Weigand, Imke Metz, Wolfgang Brück, Hans Lassmann, Monica Giraldo-Chica, John D Port, Claudia F Lucchinetti

Journal: Annals of Clinical and Translational Neurology

Year Published: 2022

Objective: In this observational study on a cohort of biopsy-proven central nervous system demyelinating disease consistent with MS, we examined the relationship between early-active demyelinating lesion immunopattern (IP) with subsequent clinical course, radiographic progression, and cognitive […]

Central auditory tests track cognitive function in those with HIV

Authors: Christopher Niemczak, Abigail Fellows, Jonathan Lichtenstein, Travis White-Schwoch, Albert Magohe, Jiang Gui, Jed Wilbur, Odile Clavier, Enica Massawe, Ndeserua Moshi, Micheal Boivin, Nina Kraus, Jay Buckey

Journal: JMIR Formative Research

Year Published: 2021

Background: The development of neurocognitive deficits in those infected with human immunodeficiency virus (HIV) is a significant public health problem. Previous cross-sectional studies show that performance on central auditory tests (CATs) correlates with cognitive test results […]

Neurocognitive effects of acute choline supplementation in low, medium and high performer healthy volunteers

Authors: Verner Knott, Sara de la Salle, Joelle Choueiry, Danielle Impey, Dylan Smith, Meaghan Smith, Elise Beaudry, Salman Saghir, Vadim Ilivitsky, Alain Labelle

Journal: Pharmacology Biochemistry and Behavior

Year Published: 2015

Novel pharmacological treatments targeting alpha 7 nicotinic acetylcholine receptor (α7 nAChR) hypofunction in schizophrenia have shown mixed success in ameliorating cognitive impairments associated with this disorder. Choline, a selective agonist at α7 receptors is increased with […]

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