The effect of histidine on mental fatigue and cognitive performance in subjects with high fatigue and sleep disruption scores
Our previous study reported that a dried bonito broth known in Japan as ‘dashi’ improved or ameliorated mood states, including fatigue, during the daily lives of human subjects. Histidine is an amino acid that is present […]
An Open Study of Sulforaphane-rich Broccoli Sprout Extract in Patients with Schizophrenia
Objective: Schizophrenia is a mental disorder characterized by severe cognitive impairment. Accumulating evidence suggests a role for oxidative stress in the pathophysiology of schizophrenia. Sulforaphane (SFN) extracted from broccoli sprout is an agent with potent anti-oxidant […]
Practice effects associated with the repeated assessment of cognitive function using the CogState battery at 10-minute, one week and one month test-retest intervals
There are many situations in which cognitive tests need to be administered on more than two occasions and at very brief test-retest intervals to detect change in group performance. However, previous literature has not specifically addressed […]
Validity of a brief computerized cognitive screening test in dementia
Background: While preliminary evidence supports the criterion validity of the CogState computerized brief battery in mild cognitive impairment (MCI) and Alzheimer disease (AD), definitive validation studies examining a wider range of dementia-related disorders relative to conventional […]
Qualitative similarities in cognitive impairment associated with 24 h of sustained wakefulness and a blood alcohol concentration of 0.05%
Previous studies that have quantified fatigue-related cognitive impairment as blood alcohol concentration (BAC) equivalents have been limited by two issues: the effect of practice on tests of cognition and, more importantly, the statistic used to quantify […]
