cognitive impairment

Decreased serum levels of mature brain-derived neurotrophic factor (BDNF), but not its precursor proBDNF, in patients with major depressive disorder

Authors: Taisuke Yoshida, Masatomo Ishikawa, Tomihisa Niitsu, Michiko Nakazato, Hiroyuki Watanabe, Tetsuya Shiraishi, Akihiro Shiina, Tasuku Hashimoto, Nobuhisa Kanahara, Tadashi Hasegawa, Masayo Enohara, Atsushi Kimura, Masaomi Iyo, Kenji Hashimoto

Journal: Public Library of Science One

Year Published: 2012

Background: Meta-analyses have identified serum levels of brain-derived neurotrophic factor (BDNF) as a potential biomarker for major depressive disorder (MDD). However, at the time, commercially available human ELISA kits are unable to distinguish between proBDNF (precursor […]

Reliability and validity of the CogState battery Chinese language version in schizophrenia

Authors: Na Zhong, Haifeng Jiang, Jin Wu, Hong Chen, Shuxing Lin, Yan Zhao, Jiang Du, Xiancang Ma, Ce Chen, Chengge Gao, Kenji Hashimoto, Min Zhao

Journal: Public Library of Science One

Year Published: 2013

Background: Cognitive impairment in patients with schizophrenia is a core symptom of this disease. The computerized CogState Battery (CSB) has been used to detect seven of the most common cognitive domains in schizophrenia. The aim of […]

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