cognitive impairment

Cognitive Profile and Relationship with Quality of Life and Psychosocial Functioning in Mood Disorders

Authors: Robson Zazula, Mohammadreza Mohebbi, Seetal Dodd, Olivia M Dean, Michael Berk, Heber Odebrecht Vargas, Sandra Odebrecht Vargas Nunes

Journal: Archives of Clinical Neuropsychology

Year Published: 2022

Background: Comparisons between healthy controls (HCs) and individuals with mood disorders have shown more cognitive dysfunction among the latter group, in particular in bipolar disorder (BD). This study aimed to characterize the pattern of cognitive function […]

Cognition-immune interactions between executive function and working memory, tumour necrosis factor-alpha (TNF-alpha) and soluble TNF receptors (sTNFR1 and sTNFR2) in bipolar disorder

Authors: Robson Zazula, Seetal Dodd, Olivia M Dean, Michael Berk, Chiara C Bortolasci, Waldiceu A Verri Jr, Heber O Vargas, Sandra O V Nunes

Journal: The World Journal of Biological Psychiatry

Year Published: 2022

Objectives: This study examined cognition-immune interactions, specifically executive function, working memory, peripheral levels of tumour necrosis factor-alpha (TNF-α), and soluble tumour necrosis factor receptors-1 and -2 (sTNFR1 and 2) levels in bipolar disorder (BD) patients in […]

A cortical thinning signature to identify World Trade Center responders with possible dementia

Authors: Sean A P Clouston, Minos Kritikos, Yael Deri, Megan Horton, Alison C Pellecchia, Stephanie Santiago-Michels, Melissa A Carr, Sam Gandy, Mary Sano, Evelyn J Bromet, Roberto G Lucchini, Benjamin J Luft

Journal: Intelligence-based Medicine

Year Published: 2021

Introduction: World Trade Center (WTC) responders have a high risk of early-onset cognitive impairment (CI), but little is known about the etiology including the extent to which CI in WTC responders is accompanied by cortical atrophy […]

Selective hippocampal subfield volume reductions in World Trade Center responders with cognitive impairment

Authors: Yael Deri, Sean A P Clouston, Christine DeLorenzo, John D Gardus 3rd, Megan Horton, Cheuk Tang, Alison C Pellecchia, Stephanie Santiago-Michels, Melissa A Carr, Sam Gandy, Mary Sano, Evelyn J Bromet, Roberto G Lucchini, Benjamin J Luft

Journal: Alzheimer's & Dementia

Year Published: 2021

Introduction: The objective of this study was to investigate associations between dementia in World Trade Center (WTC) responders and in vivo volumetric measures of hippocampal subfield volumes in WTC responders at midlife. Methods: A sample of […]

A deep learning approach for monitoring parietal-dominant Alzheimer’s disease in World Trade Center responders at midlife

Authors: Allen P F Chen, Sean A P Clouston, Minos Kritikos, Lauren Richmond, Jaymie Meliker, Frank Mann, Stephanie Santiago-Michels, Alison C Pellecchia, Melissa A Carr, Pei-Fen Kuan, Evelyn J Bromet, Benjamin J Luft

Journal: Brain Communications

Year Published: 2021

Little is known about the characteristics and causes of early-onset cognitive impairment. Responders to the 2001 New York World Trade Center disaster represent an ageing population that was recently shown to have an excess prevalence of […]

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