older adults

Evaluating Physical Frailty as a Marker of Cognitive Health in Older Adults without Dementia

Authors: Youngmin Cho, Jing Huang, Sofia Liu, Nada Lukkahatai, Jessica Gill, Junxin Li

Journal: Journal of Geriatric Psychiatry and Neurology

Year Published: 2026

Physical frailty is associated with adverse health outcomes in older adults, including cognitive decline; however, the underlying biological and pathophysiological mechanisms linking frailty to neuropathological biomarkers remain underexplored, particularly in older adults without dementia. This study […]

Embolic protection in patients undergoing transaortic transcatheter aortic valve replacement: initial experience with the TriGuard HDH embolic deflection device

Authors: Francisco Campelo-Parada, Ander Regueiro, Eric Dumont, Robert DeLarochellière, Jean-Michel Paradis, Siamak Mohammadi, Daniel Doyle, Josep Rodés-Cabau

Journal: Journal of Cardiac Surgery

Year Published: 2016

Background: Stroke remains one of the most worrisome complications following transcatheter aortic valve replacement (TAVR). This pilot study evaluates the safety, feasibility, and exploratory efficacy of the TriGuard HDH embolic deflection device (Keystone Heart Ltd., Caesarea, […]

The beneficial effects of cognitive training with simple calculation and reading aloud in an elderly postsurgical population: study protocol for a randomized controlled trial

Authors: Kay Kulason, Rui Nouchi, Yasushi Hoshikawa, Masafumi Noda, Yoshinori Okada, Ryuta Kawashima

Journal: Trials Journal

Year Published: 2016

Background: This project proposes a pilot study to investigate the positive healing effects of cognitive training with simple arithmetic and reading aloud on elderly postsurgical patients. Elderly patients undergoing surgery have an increased risk of Postoperative […]

Effects of a Supplement Containing Apoaequorin on Verbal Learning in Older Adults in the Community

Authors: Daniel L Moran, Mark Y Underwood, Taylor A Gabourie, Kenneth C Lerner

Journal: Advances in Mind-Body Medicine

Year Published: 2016

Context: The changes in verbal learning and working memory that often occur with aging may result in reduced social and intellectual interactions. These changes significantly affect an individual’s quality of life. As humans age, the body’s […]

Evaluation of a Self-Administered Computerized Cognitive Battery in an Older Population

Authors: Alain K Koyama, Kaitlin A Hagan, Olivia I Okereke, Marc G Weisskopf, Bernard Rosner, Francine Grodstein

Journal: Neuroepidemiology

Year Published: 2015

Objective: The aim of this study is to assess the utility of the Cogstate self-administered computerized neuropsychological battery in a large population of older men. Methods: We invited 7,167 men (mean age of 75 years) from […]

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