A Data-Driven Cognitive Composite Sensitive to Amyloid-β for Preclinical Alzheimer’s Disease
Background: Integrating scores from multiple cognitive tests into a single cognitive composite has been shown to improve sensitivity to detect AD-related cognitive impairment. However, existing composites have little sensitivity to amyloid-β status (Aβ +/-) in preclinical […]
Participant completion of longitudinal assessments in an online cognitive aging registry: The role of medical conditions
Introduction: This study aimed to understand whether older adults’ longitudinal completion of assessments in an online Alzheimer’s disease and related dementias (ADRD)-related registry is influenced by self-reported medical conditions. Methods: Brain Health Registry (BHR) is an […]
Reliability, Validity, and User-Experience of Remote Unsupervised Computerized Neuropsychological Assessments in Community-Living 55- to 75-Year-Olds
Background: Self-administered computerized neuropsychological assessments (CNAs) provide lower cost, more accessible alternatives to traditional in-person assessments but lack critical information on psychometrics and subjective experience of older adults in remote testing environments. Objective: We used an […]
Severity of Ongoing Post-Concussive Symptoms as a Predictor of Cognitive Performance Following a Pediatric Mild Traumatic Brain Injury
Objective: This study aimed to examine the predictors of cognitive performance in patients with pediatric mild traumatic brain injury (pmTBI) and to determine whether group differences in cognitive performance on a computerized test battery could be […]
Cognitive complaints by hematopoietic cell transplantation recipients and change in neuropsychological performance over time
Purpose: Hematopoietic stem cell transplant (HSCT) recipients are at risk for cognitive decline. Cross-sectional studies show patients’ complaints of cognitive decline do not correlate well with concurrently measured objective neuropsychological performance, but rather with emotional variables […]
