Visual Memory Deficits in Middle-Aged APOEɛ4 Homozygotes Detected Using Unsupervised Cognitive Assessments

Authors: Yen Ying Lim, Matthew P Pase, Rachel F Buckley, Nawaf Yassi, Lisa Bransby, Christopher Fowler, Simon M Laws, Colin L Masters, Paul Maruff

Journal: Journal of Alzheimer's Disease

Year Published: 2021

Background: The apolipoprotein E (APOE) ɛ4 allele is associated with dose-response effects on cognitive dysfunction and dementia risk in older adults. However, its effects on cognition in middle-aged adults remains unclear. Objective: We examined effects of […]

A Comparison of Computerized Versus Pen-and-Paper Cognitive Tests for Monitoring Electroconvulsive Therapy-Related Cognitive Side Effects

Authors: Donel M Martin, Divya Kumar, Ada Wong, Colleen K Loo

Journal: The Journal of ECT

Year Published: 2020

Objective: Cognitive side effects are a common unintended outcome of electroconvulsive therapy (ECT). Routine cognitive assessment is important for monitoring patient outcomes, although it can pose challenges in busy clinical settings. Computerized cognitive testing has advantages […]

Changes in functional connectivity in people with HIV switching antiretroviral therapy

Authors: Sofia Toniolo, Mara Cercignani, Borja Mora-Peris, Jonathan Underwood, Jasmini Alagaratnam, Marco Bozzali, Marta Boffito, Mark Nelson, Alan Winston, Jaime H Vera

Journal: Journal of Neuro Virology

Year Published: 2020

We assessed changes in functional connectivity by fMRI (functional magnetic resonance imaging) and cognitive measures in otherwise neurologically asymptomatic people with HIV (PWH) switching combination antiretroviral therapy (cART). In a prospective study (baseline and follow-up after […]

Diagnostic and Prognostic Accuracy of the Cogstate Brief Battery and Auditory Verbal Learning Test in Preclinical Alzheimer’s Disease and Incident Mild Cognitive Impairment: Implications for Defining Subtle Objective Cognitive Impairment

Authors: Nikki H Stricker, Emily S Lundt, Sabrina M Albertson, Mary M Machulda, Shehroo B Pudumjee, Walter K Kremers, Clifford R Jack, David S Knopman, Ronald C Petersen, Michelle M Mielke

Journal: Journal of Alzheimer's Disease

Year Published: 2020

Background: There are detectable cognitive differences in cognitively unimpaired (CU) individuals with preclinical Alzheimer’s disease (AD). Objective: To determine whether cross-sectional performance on the Cogstate Brief Battery (CBB) and Auditory Verbal Learning Test (AVLT) could identify […]

Longitudinal Comparison of in Clinic and at Home Administration of the Cogstate Brief Battery and Demonstrated Practice Effects in the Mayo Clinic Study of Aging

Authors: N H Stricker, E S Lundt, E C Alden, S M Albertson, M M Machulda, W K Kremers, D S Knopman, R C Petersen, M M Mielke

Journal: The Journal of Prevention of Alzheimer's Disease

Year Published: 2020

Background: The Cogstate Brief Battery (CBB) is a computerized cognitive assessment that can be completed in clinic or at home. Design/Objective: This retrospective study investigated whether practice effects / performance trajectories of the CBB differ by […]

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