memantine

Memantine for Prevention of Cognitive Late Effects in Children and Adolescents Receiving Radiotherapy for Brain Tumors: A Randomized, Controlled, Pilot Trial

Authors: Heather M Conklin, Raja B Khan, Jason M Ashford, Christina Owens, Andrea Simmons, Christina Bosley, Chia-Wei Hsu, Haitao Pan, Amar Gajjar, Thomas E Merchant

Journal: International Journal of Radiation Oncology Biology Physics

Year Published: 2026

Background: Children receiving irradiation for brain tumors are at significant risk for cognitive deficits that notably impact quality of life. This is the first randomized, controlled, investigation of the feasibility, acceptability, and preliminary efficacy of memantine […]

Memantine for patients with Parkinson’s disease dementia or dementia with Lewy bodies: a randomised, double-blind, placebo-controlled trial

Authors: Murat Emre, Magda Tsolaki, Ubaldo Bonuccelli, Alain Destée, Eduardo Tolosa, Alexandra Kutzelnigg, Andrés Ceballos-Baumann, Slobodan Zdravkovic, Anna Bladström, Roy Jones, 11018 Study Investigators

Journal: Neurology

Year Published: 2010

Background: Previous studies have suggested that patients with Lewy-body-related dementias might benefit from treatment with the N-methyl D-aspartate receptor antagonist memantine, but further data are needed. Therefore, the efficacy and safety of memantine were investigated in […]

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