insomnia

Sleep symptomatology is associated with greater subjective cognitive concerns: Findings from the community-based Healthy Brain Project

Authors: Jessica Nicolazzo, Katharine Xu, Alexandra Lavale, Rachel Buckley, Nawaf Yassi, Garun S Hamilton, Paul Maruff, Andree-Ann Baril, Yen Ying Lim, Matthew P Pase

Journal: Sleep

Year Published: 2021

Study objectives To examine if sleep symptomatology was associated with subjective cognitive concerns or objective cognitive performance in a dementia-free community-based sample. Methods A total of 1421 middle-aged participants (mean±standard deviation = 57±7; 77% female) from […]

Increased Dolutegravir Peak Concentrations in People Living With Human Immunodeficiency Virus Aged 60 and Over, and Analysis of Sleep Quality and Cognition

Authors: ER Elliot, X Wang, S Singh, B Simmons, JH Vera, RF Miller, C Fitzpatrick, G Moyle, M McClure, M Boffito

Journal: Clinical Infectious Diseases

Year Published: 2019

Background: Demographic data show an increasingly aging human immunodeficiency virus (HIV) population worldwide. Recent concerns over dolutegravir-related neuropsychiatric toxicity have emerged, particularly amongst older people living with HIV (PLWH). We describe the pharmacokinetics (PK) of dolutegravir […]

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