Central auditory tests track cognitive function in those with HIV
Background: The development of neurocognitive deficits in those infected with human immunodeficiency virus (HIV) is a significant public health problem. Previous cross-sectional studies show that performance on central auditory tests (CATs) correlates with cognitive test results […]
Correlation between computerised and standard cognitive testing in people with HIV and HIV-negative individuals
We investigated the correlations and agreement between cognitive assessments made using a computerised (CogState™, six domains) and a standard pen-and-paper battery (five domains) in PWH and lifestyle-similar HIV-negative individuals. Demographically adjusted domain and global T-scores were […]
Cognitive ageing is premature among a community sample of optimally treated people living with HIV
Objectives: Evidence of premature cognitive ageing amongst people living with HIV (PLHIV) remains controversial due to previous research limitations including underpowered studies, samples with suboptimal antiretroviral access, varying rate of virological control, high rate of AIDS, […]
Changes in functional connectivity in people with HIV switching antiretroviral therapy
We assessed changes in functional connectivity by fMRI (functional magnetic resonance imaging) and cognitive measures in otherwise neurologically asymptomatic people with HIV (PWH) switching combination antiretroviral therapy (cART). In a prospective study (baseline and follow-up after […]
Depression, lifestyle factors and cognitive function in people living with HIV and comparable HIV-negative controls
Objectives: We investigated whether differences in cognitive performance between people living with HIV (PLWH) and comparable HIV-negative people were mediated or moderated by depressive symptoms and lifestyle factors. Methods: A cross-sectional study of 637 ‘older’ PLWH […]
