Online study partner-reported cognitive decline in the Brain Health Registry
Introduction Methods for efficiently identifying cognitive decline and Alzheimer’s disease (AD) are a critical unmet need. The goal of this work was to validate novel online study partner (SP)-reported outcomes to identify cognitive decline in older […]
Indication of Cognitive Change and Associated Risk Factor after Thoracic Surgery in the Elderly: A Pilot Study
Background: This pilot study investigated the effects of partial pulmonary lobectomy lung surgery on cognitive functions of elderly Japanese patients. It is recognized that elderly patients undergoing surgery have increased risk of Postoperative Cognitive Decline (POCD), […]
Episodic memory decline predicts cortical amyloid status in community-dwelling older adults
Intra-individual decline in memory and cognition is characteristic of prodromal Alzheimer’s disease (AD) and may allow detection of very early AD pathology. Episodic memory task scores on a brief computerized cognitive battery (CogState) were prospectively evaluated […]
Intraindividual cognitive decline using a brief computerized cognitive screening test
Background: Progressive intraindividual decline in memory and cognition is characteristic of dementia and may be useful in detecting very early Alzheimer’s disease pathology. Methods: This study evaluated the slopes of cognitive performance over a 12-month period […]
