cognitive decline

Building clinically relevant outcomes across the Alzheimer’s disease spectrum

Authors: Dorene M. Rentz, Alette M. Wessels, Ananth V. Annapragada, Anna‐Karin Berger, Chris J. Edgar, Michael Gold, David S. Miller, Christopher Randolph, J. Michael Ryan, Glen Wunderlich, Megan Canniere Zoschg, Dominic Trépel, David S. Knopman, Adam M. Staffaroni, Lisa J. Bain, Maria C. Carrillo, Christopher J. Weber

Journal: Alzheimer's & Dementia

Year Published: 2021

Demonstrating that treatments are clinically meaningful across the Alzheimer’s disease (AD) continuum is critical for meeting our goals of accelerating a cure by 2025. While this topic has been a focus of several Alzheimer’s Association Research […]

Medical cannabis and cognitive performance in middle to old adults treated for chronic pain

Authors: Sharon R Sznitman, Simon Vulfsons, David Meiri, Galit Weinstein

Journal: Drug and Alcohol Review

Year Published: 2021

Introduction and aims: Cannabis exposure is becoming more common in older age but little is known about how it is associated with brain health in this population. This study assesses the relationship between long-term medical cannabis […]

The Effect of Cochlear Implants on Cognitive Function in Older Adults: Initial Baseline and 18-Month Follow Up Results for a Prospective International Longitudinal Study

Authors: Julia Sarant, David Harris, Peter Busby, Paul Maruff, Adrian Schembri, Richard Dowell and Robert Briggs

Journal: Frontiers in Neuroscience

Year Published: 2019

Abstract In older adults, hearing loss is independently associated with an increased rate of cognitive decline, and has been identified to be a modifiable risk factor for dementia. The mechanism underlying the cognitive decline associated with […]

Online study partner-reported cognitive decline in the Brain Health Registry

Authors: Rachel L. Nosheny, Monica R. Camacho, Philip S. Insel, Derek Flenniken, Juliet Fockler, Diana Truran, Shannon Finley, Aaron Ulbricht, Paul Maruff, Kristine Yaffe, R. Scott Mackin, Michael W. Weiner, Alzheimer's Disease Neuroimaging Initiative

Journal: Alzheimer's & Dementia

Year Published: 2018

Introduction Methods for efficiently identifying cognitive decline and Alzheimer’s disease (AD) are a critical unmet need. The goal of this work was to validate novel online study partner (SP)-reported outcomes to identify cognitive decline in older […]

Indication of Cognitive Change and Associated Risk Factor after Thoracic Surgery in the Elderly: A Pilot Study

Authors: Kay Kulason, Rui Nouchi, Yasushi Hoshikawa, Masafumi Noda, Yoshinori Okada, Ryuta Kawashima

Journal: Frontiers in Aging Neuroscience

Year Published: 2018

Background: This pilot study investigated the effects of partial pulmonary lobectomy lung surgery on cognitive functions of elderly Japanese patients. It is recognized that elderly patients undergoing surgery have increased risk of Postoperative Cognitive Decline (POCD), […]

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