Memantine for Prevention of Cognitive Late Effects in Children and Adolescents Receiving Radiotherapy for Brain Tumors: A Randomized, Controlled, Pilot Trial
Background: Children receiving irradiation for brain tumors are at significant risk for cognitive deficits that notably impact quality of life. This is the first randomized, controlled, investigation of the feasibility, acceptability, and preliminary efficacy of memantine […]
Preliminary exploration of a computerized cognitive battery and comparison with traditional testing in patients with high-grade glioma
Background: Cognitive function is an important outcome measure in many brain tumor clinical trials, and investigators are interested in employing the most efficient methods of cognitive assessment for this purpose. Computerized testing can be appealing because […]
Computerized assessment of cognitive impairment among children undergoing radiation therapy for medulloblastoma
Purpose: Advantages to computerized cognitive assessment include increased precision of response time measurement and greater availability of alternate forms. Cogstate is a computerized cognitive battery developed to monitor attention, memory, and processing speed. Although the literature […]
