Depression

The latest from Cogstate, leaders in optimizing the measurement of cognition

Dementia With Lewy Bodies Predicted By Autonomic Testing in Major Depressive Disorder

April 1, 2016

As the third leading type of dementia, behind only Alzheimer’s disease and vascular dementia, dementia with Lewy bodies (DLB) is often linked with symptoms similar to Parkinson’s disease. Present in several other brain disorders, Lewy bodies are abnormal aggregates of protein, primarily alpha-synuclein. Detecting Lewy bodies early before dementia-related symptoms emerge is important to the […]

FDA Advisory Committee Support of Brintellix for Cognitive Dysfunction in Depression: A Re-consideration of What Makes a Clinically Meaningful Cognitive Deficit

February 12, 2016

Takeda and Lundbeck announced recently that the U.S. FDA Psychopharmacologic Drugs Advisory Committee voted 8 to 2 that the companies presented substantial evidence to support the effectiveness of Brintellix (vortioxetine) for treating aspects of cognitive dysfunction in adults with Major Depressive Disorder (MDD). There has been a great deal of optimism and analysis about what […]

Early Research Suggests Ketamine Does Not Cause Neurocognitive Decline In Children

April 2, 2015

Used as an inexpensive, easy to administer anesthetic for years, the drug ketamine has been in the news lately for two related uses. While the World Health Organization has named ketamine to be an “essential medicine” that should be available to all health systems, it is also being abused by recreational drug users as a […]

Connection Found Between Anxiety, Amyloid and Cognitive Change

February 2, 2015

As we grow older, most of us have plenty on our minds that can cause some level of anxiety at times.  Worries about our family and career are part of a normal life.  However, when those feelings reach a certain level, they may combine with other changes in the brain to accelerate cognitive disorders such […]

Research Links Cognitive Impairment With Work Productivity In MDD Patients

October 8, 2014

Evidence of cognitive impairment in patients suffering from major depressive disorder (MDD) has grown recently as new research shows that episodic memory, learning and executive functions can also be affected by the condition. At this week’s ISCTM Autumn Conference in Boston, Cogstate scientists presented their findings of a subtle relationship between cognitive decline and decreased […]

Antidepressant Vortioxetine Shown To Improve Cognitive Function

June 17, 2014

In addition to the more well known emotional symptoms of depression, such as a lack of interest, low self-esteem and hopelessness, patients can also suffer from cognitive problems including memory loss, attention and poor decision making.  Finding medical treatments that can manage both sets of conditions has been difficult but a new study from Danish […]

Cognitive Dysfunction Also Present In Patients With Depression

October 5, 2013

For the 350 million people around the world who suffer from depression, having their physicians, family and friends truly understand their battle has been an ongoing struggle.  Common symptoms such as change in sleep, appetite and energy combined with a lack of interest, low self-esteem and hopelessness create an image of depression being just an […]