Measuring Cognition in Pediatric Oncology Trials: Topics, Trends and Key Takeaways from the Children’s Oncology Group (COG) Fall Meeting
October 11, 2018
Data from Brain Health Registry show utility of online unsupervised cognitive testing using the Cogstate Brief Battery in older adults
August 10, 2018
Research efforts for therapies that slow or prevent AD involve large clinical trials that require participants who have the disease but who are experiencing only very early signs of cognitive decline. To find optimal study candidates, large pools of potential participants need to be screened in the most efficient way possible. The use of online health registries shows great promise for addressing this important need.
Trial Design of PCSK9-inhibitor, Evolocumab, in Pediatric Patients with Heterozygous Familial Hypercholesterolemia
June 18, 2018
Prof. Paul Maruff discusses a published paper detailing the design of a study investigating the PCSK9-inhibitor, evolocumab, in pediatric patients with heterozygous familial hypercholesterolemia.
Structured Exercise Program Improves Cognitive Functioning for Patients with First-Episode Psychosis
June 6, 2018
Swedish and Australian researchers published the effects of an organized exercise program on a group of adults diagnosed with first-episode psychosis. Results from the Cogstate Brief Battery showed a positive relationship between exercise and the cognitive functioning of these patients.
Study Shows Similar Symptom Profile in Ketamine Dependence with Persistent Psychosis and Schizophrenia
March 28, 2018
Researchers measured psychosis (PANSS) and cognitive impairments (Cogstate), and the symptom profile of persisting psychosis due to chronic heavy ketamine abuse resembled that of schizophrenia.
February 11, 2018
Results from the neuropsychological test battery showed no difference between APOE ε4 allele carriers and the non-carriers, suggesting that a healthy lifestyle can slow cognitive decline, even for those with the genetic risk.
January 17, 2018
Even when employing the most intensive rater training program, many raters may still make errors in administering and scoring some psychometric tests and rating scales in clinical trials. Central Monitoring helps ensure the highest possible data quality through rigorous expert review.
January 10, 2018
Research shows that drinking the appropriate amount of water improves cognitive performance, as seen from results on Cogstate computerized cognitive tests.
December 6, 2017
Cogstate computerized cognitive tests have been designed and validated to withstand the numerous operational challenges of conducting clinical trials — dramatically increasing the sensitivity and specificity of the measurement of cognition in clinical research.
November 20, 2017
Cogstate CSO, Prof. Paul Maruff, discusses the recent Clinical Trials in Alzheimer’s Disease (CTAD) conference and the exciting scientific contributions from Cogstate.