Effect of hyperbilirubinaemia on neurocognitive, renal, bone and cardiovascular markers in HIV infection treated with boosted protease inhibitors
Introduction: Use of some protease inhibitors (PI) is associated with unconjugated hyperbilirubinaemia (HBR), due to inhibition of UGT1A1. As observed in Gilbert’s syndrome, HBR may have antioxidant and anti-inflammatory effects. Inflammation may be relevant to neurocognitive […]