Association of C-reactive protein and metabolic risk with cognitive effects of lurasidone in patients with schizophrenia
Background: Accumulating evidence has implicated insulin resistance and inflammation in the pathophysiology of cognitive impairments associated with neuropsychiatric disorders. This post-hoc analysis based on a placebo-controlled trial investigated the effect of inflammation (indexed by CRP) and […]
Relation between retinal vascular abnormalities and working memory impairment in patients with schizophrenia and bipolar disorder
Emerging evidence indicates abnormal retinal micro-vasculature in schizophrenia (SCZ) and bipolar disorder (BD) and its relation to cognitive functions. However, the association of these abnormalities with the cognitive deficits in these disorders has not been examined till date.
Effects of transcranial direct current stimulation on cognition and symptoms in Chinese patients with schizophrenia
There is preliminary evidence that transcranial direct current stimulation(tDCS) may improve symptoms and cognitive function in schizophrenia, but the generalizability of these results needs further investigation. We present a study of the effects of active vs. […]
Cognitive capacity similarly predicts insight into symptoms in first- and multiple-episode psychosis
Background: Lack of insight is a frequent characteristic of psychotic disorders, both in patients who recently experienced a first episode of psychosis (FEP) and those who experience recurrent multiple episodes (MEP). Insight is a multifaceted construct: […]
Exercise effects on cognitive functioning in young adults with first-episode psychosis: FitForLife
Background Exercise has mood-enhancing effects and can improve cognitive functioning, but the effects in first-episode psychosis (FEP) remain understudied. We examined the feasibility and cognitive effects of exercise in FEP. Method Multi-center, open-label intervention study. Ninety-one […]
