proof of concept

Cognitive Go/No-Go decision-making criteria in Alzheimer’s disease drug development

Authors: Alette M. Wessels, Chris J. Edgar, Pradeep J. Nathan, Eric R. Siemers, Paul Maruff, John Harrison

Journal: Drug Discovery Today

Year Published: 2021

Go/No-Go decision making in early phase clinical trials is challenging for drug developers working in Alzheimer’s disease. Recent negative trial results have been attributed to a lack of efficacy and important safety concerns. Furthermore, demonstrated target […]

Back to Publications