plasma biomarkers

Scalable Markers for Early Cognitive Decline: Plasma p-tau217, Subjective Cognitive Concerns, and Digital Testing: Results from the A4/LEARN studies

Authors: Babak Khorsand, Devin Teichrow, Elham Ghanbarian, Lukai Zheng, S Ahmad Sajjadi, Crystal M Glover, Joshua D Grill, Laura A Rabin, Ali Ezzati

Journal: medRxiv

Year Published: 2025

Background and objectives: Although amyloid positron emission tomography (PET) and Cerebrospinal fluid (CSF) biomarkers remain the standard for confirming Alzheimer’s disease (AD) pathology, their use is impractical for screening or routine prognostic assessment. Plasma phosphorylated tau […]

Cognitive performance and blood biomarkers: Insights into their relationship and predicting high Amyloid Probability Score in cognitively impaired older adults

Authors: Thi Quynh Tho Chu, Kohei Morimoto, Hisatomo Kowa

Journal: Journal of Alzheimer's Disease

Year Published: 2025

Background: Understanding associations between cognitive performance and blood biomarkers supports diagnosis and treatment of Alzheimer’s disease (AD); however, this relationship remains unclear. Objective: Exploring associations between the Amyloid Probability Score (APS; PrecivityAD® blood test) and cognitive […]

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