neurocognitive assessments

Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use

Authors: Oksana Pogoryelova, Jan Smeitink, Herma Renkema, Rosabeth White, Frankie Barton, Rachel Lyon, Jane Newman, Aye Moe, Yi Shiau Ng, Grainne Siobhan Gorman

Journal: Annals of Clinical and Translational Neurology

Year Published: 2026

Background: Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers […]

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