The selective neurokinin 3 antagonist AZD2624 does not improve symptoms or cognition in schizophrenia: a proof-of-principle study.

Authors: Desai DG, Kanes SJ, Litman RE, Simpson T, Smith MA, Sweitzer D

Journal: Journal of Clinical Psychopharmacology

Problems with the efficacy of second-generation antipsychotics on negative symptoms and cognition have highlighted the need for further development of drugs targeting central nervous system neurotransmitter systems other than dopamine. One target in development is neurokinin […]

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