Evaluating Physical Frailty as a Marker of Cognitive Health in Older Adults without Dementia
Physical frailty is associated with adverse health outcomes in older adults, including cognitive decline; however, the underlying biological and pathophysiological mechanisms linking frailty to neuropathological biomarkers remain underexplored, particularly in older adults without dementia. This study […]
Cognitive Performance in Late Midlife as a Predictor of Frailty from Late Midlife into Old Age: A Longitudinal Birth Cohort Study
Introduction: Cognitive decline is cross-sectionally associated with frailty in older adults. However, the longitudinal associations between cognitive performance in late midlife and subsequent frailty are less well understood. Methods: Participants of the Helsinki Birth Cohort Study […]
Prevalence and risk factors of cognitive frailty in people with HIV
Background: Cognitive frailty (CF, the simultaneous presence of frailty and cognitive impairment) is recognized as a significant predictor of several adverse health outcomes. The objective of this study was to describe prevalence and risk factors for […]
The effects of an extensive exercise programme on the progression of Mild Cognitive Impairment (MCI): study protocol for a randomised controlled trial
Background: Exercise interventions to prevent dementia and delay cognitive decline have gained considerable attention in recent years. Human and animal studies have demonstrated that regular physical activity targets brain function by increasing cognitive reserve. There is […]
