An 18-month follow-up investigation of motor coordination and working memory in primary school children
The aim of the current study was to examine the relationship between motor coordination and visual working memory in children aged 5-11 years. Participants were 18 children with movement difficulty and 41 control children, assessed at […]
A randomized, double-blind, placebo-controlled, 16-week study of the H3 receptor antagonist, GSK239512 as a monotherapy in subjects with mild-to-moderate Alzheimer’s disease
Introduction: Histaminergic H3 receptors may play a role in modulating cholinergic and monoaminergic neurotransmission. This Phase II study evaluated the efficacy and safety of GSK239512, a highly potent, brain penetrant H3 receptor antagonist as monotherapy treatment […]