Amyloid-Related Memory Decline in Preclinical Alzheimer’s Disease Is Dependent on APOE ε4 and Is Detectable over 18-Months.

Authors: Christine Thai, Yen Ying Lim, Victor L Villemagne, Simon M Laws, David Ames, Kathryn A Ellis, Stephanie R Rainey-Smith, Ralph N Martins, Colin L Masters, Christopher C Rowe, Paul Maruff, Australian Imaging, Biomarkers and Lifestyle (AIBL) Research Group

Journal: PloS One

Year Published: 2015

High levels of β-amyloid (Aβ) in the brain and carriage of the APOE ε4 allele have each been linked to cognitive impairment in cognitively normal (CN) older adults. However, the relationship between these two biomarkers and […]

Detection of MCI in the clinic: Evaluation of the sensitivity and specificity of a computerised test battery, the Hopkins Verbal Learning Test and the MMSE

Authors: Celeste A de Jager, Anne-Claire M C Schrijnemaekers, Thurza E M Honey, Marc M Budge

Journal: Age and Ageing

Year Published: 2009

Introduction: The sensitive detection of mild cognitive impairment (MCI) in older adults is an important problem that requires objective assessment. We evaluated whether the computerised cognitive test battery, CogState, was as sensitive to MCI as two […]

Computerized Neurocognitive Test (CNT) in Mild Cognitive Impairment and Alzheimer’s Disease

Authors: Maira Okada de Oliveira, Sonia Maria Dozzi Brucki

Journal: Dementia & Neuropsychologia

Year Published: 2014

Currently, computerized batteries are of great value in detecting cognitive impairment. This aim of this review was to compare the computerized neurocognitive batteries used in most studies with cognitive decline over the last 10 years. Using […]

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