Association between DATSCAN-derived dopaminergic activity and cognitive performance and quality of life in Parkinson’s disease: A cross-sectional study
Background: Parkinson’s disease (PD) is a neurodegenerative disorder characterized by motor and non-motor symptoms that substantially affect quality of life (QoL). While dopaminergic dysfunction is central to PD pathology, the cross-sectional relationship between striatal dopaminergic activity […]
Can vigorous physical activity mitigate the effect of systemic inflammation on cognitive performance? Results from a large older community dwelling population in The Netherlands
Background: Elevated systemic inflammation is associated with poorer cognitive function, while vigorous physical activity enhances cognition. Objective: This study examines whether physical activity moderates the relationship between systemic inflammation and cognitive performance. Methods: We analyzed 24,661 […]
A new injury prevention program ‘FUNBALL’ improves cognitive performance of young football (soccer) players: A cluster randomized controlled trial
The youth football injury prevention program ‘FUNBALL’ contains exercises requiring high cognitive demands, which are performed concurrently to the training of the respective motor task. This study evaluates whether the program increases cognitive performances of young […]
Does cannabis affect cognitive functioning in patients with schizophrenia?
Introduction: Cannabis use impairs cognitive performance in healthy subjects; several studies have shown improved cognitive outcomes in schizophrenic patients using cannabis. The aim of this study was to evaluate the effects of cannabis use on cognitive […]
Multidomain modifiable dementia risk factors are associated with poorer cognition in midlife
Objective: Studies of modifiable dementia risk factors (MDRFs) generally consider MDRFs individually, despite strong evidence that they co-occur in adult populations. In a large sample of middle-aged adults, this study aimed to determine the frequency and […]
