Clinical neurology

Cognitive function at the time of focal epilepsy diagnosis is not associated with treatment resistance

Authors: Jacob Pellinen, Stefan Sillau, Chris Morrison, Paul Maruff, Terence J O'Brien, Patricia Penovich, Jacqueline French, Kelly G Knupp, Sarah Barnard, Manisha Holmes, Manu Hegde, Andres M Kanner, Kimford J Meador

Journal: Epilepsy & Behavior

Year Published: 2025

Objective: Seizures can impact cognition both acutely and chronically. However, among those without significant comorbidities and broadly average cognition at epilepsy onset, the relationship between cognitive function at the time of diagnosis and long-term seizure control […]

Pre-treatment seizures and cognition at the time of focal epilepsy diagnosis

Authors: Jacob Pellinen, Stefan Sillau, Chris Morrison, Paul Maruff, Terence O'Brien, Patricia Penovich, Jacqueline French, Kelly G Knupp, Manisha Holmes, Sarah Barnard, Andres M Kanner, Kimford J Meador

Journal: Epilepsy & Behavior

Year Published: 2025

Objective: People with focal epilepsy experience one or more seizures prior to diagnosis. The Human Epilepsy Project (HEP) was a prospective study enrolling people with newly diagnosed focal epilepsy. It collected information including cognitive testing at […]

Engagement in online cognitive testing with the Cogstate brief battery among a multinational cohort of people with focal epilepsy

Authors: Jacob Pellinen, Stefan Sillau, Chris Morrison, Paul Maruff, Terence J O'Brien, Patricia Penovich, Jacqueline French, Kelly G Knupp, Kimford J Meador

Journal: Epilepsy and Behavior

Year Published: 2024

Objective: The Human Epilepsy Project (HEP) is a large multinational cohort study of people with newly diagnosed and treated focal epilepsy. HEP utilized the Cogstate Brief Battery (CBB) as a self-directed online assessment to examine cognitive […]

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