Cellular neuroscience

Clearance and transport of amyloid β by peripheral monocytes correlate with Alzheimer’s disease progression

Authors: Xin Huang, Chris Fowler, Yihan Li, Qiao-Xin Li, Jiaqi Sun, Yijun Pan, Liang Jin, Keyla A Perez, Céline Dubois, Yen Y Lim, Candace Drysdale, Rebecca L Rumble, Holly R Chinnery, Christopher C Rowe, Ralph N Martins, Paul Maruff, James D Doecke, Yong Lin, Abdel A Belaidi, Kevin J Barnham, Colin L Masters, Ben J Gu

Journal: Nature Communications

Year Published: 2024

Impaired clearance of amyloid β (Aβ) in late-onset Alzheimer’s disease (AD) affects disease progression. The role of peripheral monocytes in Aβ clearance from the central nervous system (CNS) is unclear. We use a flow cytometry assay […]

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