Repeat radiation with bevacizumab and minocycline in bevacizumab-refractory high grade gliomas: a prospective phase 1 trial

Authors: Adam L Cohen, Christopher J Anker, Brett Johnson, Lindsay M Burt, Dennis C Shrieve, Karen Salzman, Randy Jensen, Ken Boucher, Howard Colman

Journal: Journal of Neuro-oncology

Year Published: 2020

Introduction: There are no effective treatments for gliomas after progression on radiation, temozolomide, and bevacizumab. Microglia activation may be involved in radiation resistance and can be inhibited by the brain penetrating antibiotic minocycline. In this phase […]

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