What is the optimum thiamine dose to treat or prevent Wernicke’s encephalopathy or Wernicke-Korsakoff syndrome? Results of a randomized controlled trial
Background: The primary cause of Wernicke-Korsakoff syndrome (WKS) is thiamine deficiency, and more than 90% of cases are reported in alcohol-dependent patients. While observational studies show parenteral thiamine administration drastically reduced WKS-related mortality, relevant treatment trials […]
