Influence of amyloid and apolipoprotein E on cognitive performance in a late middle-aged cohort

Authors: Michelle M Mielke, Mary M Machulda, Clinton E Hagen, Teresa J Christianson, Rosebud O Roberts, David S Knopman, Prashanthi Vemuri, Val J Lowe, Walter K Kremers, Clifford R Jack Jr, Ronald C Petersen

Journal: Alzheimer's & Dementia

Year Published: 2015

Introduction: Few studies have examined the effects of amyloid and apolipoprotein E (APOE) genotype on cognition among middle-aged individuals. Methods: We included 464 cognitively normal, test-naïve, participants with Pittsburgh compound B positron emission tomography amyloid imaging, […]

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