PET

Applications of amyloid, tau, and neuroinflammation PET imaging to Alzheimer’s disease and mild cognitive impairment.

Authors: Chandra A, Cousins O, Dervenoulas G, Pagano G, Politis M, Valkimadi PE

Journal: Human brain mapping

Alzheimer’s disease (AD) is a devastating and progressive neurodegenerative disease for which there is no cure. Mild cognitive impairment (MCI) is considered a prodromal stage of the disease. Molecular imaging with positron emission tomography (PET) allows […]

Influence of amyloid and apolipoprotein E on cognitive performance in a late middle-aged cohort.

Authors: Christianson TJ, Hagen CE, Jack CR Jr, Knopman DS, Kremers WK, Lowe VJ, Machulda MM, Mielke MM, Petersen RC, Roberts RO, Vemuri P

Journal: Alzheimer's & Dementia

INTRODUCTION: Few studies have examined the effects of amyloid and apolipoprotein E (APOE) genotype on cognition among middle-aged individuals. METHODS: We included 464 cognitively normal, test-na├»ve, participants with Pittsburgh compound B positron emission tomography amyloid imaging, […]

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