Social cognitive and neurocognitive deficits in inpatients with unilateral thalamic lesions – pilot study.
BACKGROUND: The essential role of the thalamus in neurocognitive processes has been well documented. In contrast, relatively little is known about its involvement in social cognitive processes such as recognition of emotion, mentalizing, or empathy. THE AIM OF THE STUDY: This study was designed to compare the performance of eight patients (five males, three females, […]
Distinguishing neurocognitive functions in schizophrenia using partially ordered classification models.
Current methods for statistical analysis of neuropsychological test data in schizophrenia are inherently insufficient for revealing valid cognitive impairment profiles. While neuropsychological tests aim to selectively sample discrete cognitive domains, test performance often requires several cognitive operations or “attributes.” Conventional statistical approaches assign each neuropsychological score of interest to a single attribute or “domain” (e.g., […]
Associating functional recovery with neurocognitive profiles identified using partially ordered classification models.
Neurocognitive deficits are a core feature of schizophrenia and a significant cause of functional disability. However, targeting these deficits with new treatment approaches will only yield functional improvements if those cognitive operations that are responsible for different dimensions of functional recovery can be identified. A major challenge is that conventional neuropsychological tests, the most practical […]
Disability in life functioning is an important and poorly understood consequence of major depressive disorder (MDD). Mood symptoms do not account for the magnitude of disability resulting from MDD. Impairments in several domains of neurocognitive (NC) functioning have been shown to interfere with functionality in other psychiatric populations. These deficits, also present in MDD, may […]