mitogen-activated protein kinase inhibitor (MEKi) treatment

Impact of MEK Inhibitor Therapy on Neurocognitive Functioning in NF1

Authors: Karin S Walsh, Pamela L Wolters, Brigitte C Widemann, Allison Del Castillo, Maegan D Sady, Tess Inker, Marie Claire Roderick, Staci Martin, Mary Anne Toledo-Tamula, Kari Struemph, Iris Paltin, Victoria Collier, Kathy Mullin, Michael J Fisher, Roger J Packer

Journal: Neurology. Genetics

Year Published: 2021

Background and objectives Neurofibromatosis type 1 (NF1)-associated cognitive impairments carry significant lifelong morbidity. The lack of targeted biologic treatments remains a significant unmet need. We examine changes in cognition in patients with NF1 in the first […]

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