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Impaired visual, working, and verbal memory in first-episode, drug-naive patients with major depressive disorder in a Chinese population.

Authors: Chen C, Gao CG, Hashimoto K, Jiang WH, Li Y, Ma XC, Wang W, Wu J

Journal: Public Library of Science One

Volume & Issue: 13 & 4

DOI: 10.1371/journal.pone.0196023

Year Published: 2018

Cognitive impairment has been observed in patients with major depressive disorder (MDD). However, it remains unclear whether the deficits in specific cognitive domains are present in first-episode, drug-naïve patients or medicated patients. In the present study, using the CogState battery (CSB) Chinese language version, we evaluated the visual, working, and verbal memory in first-episode drug-naive […]

Preliminary evidence concerning the pattern and magnitude of cognitive dysfunction in major depressive disorder using cogstate measures.

Authors: Davis MT, DellaGioia N, Esterlis I, Harel B, Maruff P, Matuskey D, Pietrzak RH

Journal: Journal of Affective Disorders

Volume & Issue: 218

Page No.: 82-85

DOI: 10.1016/j.jad.2017.04.064

Year Published: 2017

BACKGROUND: Cognitive deficits are common in individuals with major depressive disorder (MDD), and are associated with treatment non-responsiveness and poorer functional outcomes. Characterization of the nature and magnitude of deficits in this population has been limited in part by lack of brief, practical, and well-validated assessment measures. The goal of this study was to use […]

Neurocognitive deficits and disability in major depressive disorder.

Authors: Berns S, Davis-Conway S, Jaeger J, Uzelac S

Journal: Psychiatry Research

Volume & Issue: 145 & 1

Page No.: 39-48

Year Published: 2006

Disability in life functioning is an important and poorly understood consequence of major depressive disorder (MDD). Mood symptoms do not account for the magnitude of disability resulting from MDD. Impairments in several domains of neurocognitive (NC) functioning have been shown to interfere with functionality in other psychiatric populations. These deficits, also present in MDD, may […]