Intra-individual variability

Moving intra-individual variability (IIV) towards clinical utility: IIV measured using a commercial testing platform

Authors: Hyein Cho, Giuseppina Pilloni, Raisa Tahsin, Pamela Best, Lauren Krupp, Cheongeun Oh, Leigh Charvet

Journal: Journal of the Neurological Sciences

Year Published: 2023

Objectives: Intra-individual variability (IIV), measured across repeated response times (RT) during continuous psychomotor tasks, is an early marker of cognitive change in the context of neurodegeneration. To advance IIV towards broader application in clinical research, we […]

Early neuropsychological markers of cognitive involvement in multiple sclerosis

Authors: Tehila Eilam-Stock, Michael T Shaw, Lauren B Krupp, Leigh E Charvet

Journal: Journal of Neurological Sciences

Year Published: 2021

Background Cognitive impairment due to multiple sclerosis (MS) is common and often limits occupational functioning, contributes to disability, and reduces quality of life. Early detection of cognitive involvement in MS is critical for treatment planning and […]

Back to Publications