HIV

The Relationship Between Central Auditory Tests and Neurocognitive Domains in Adults Living With HIV

Authors: Christopher E Niemczak, Jonathan D Lichtenstein, Albert Magohe, Jennifer T Amato, Abigail M Fellows, Jiang Gui, Michael Huang, Catherine C Rieke, Enica R Massawe, Michael J Boivin, Ndeserua Moshi, Jay C Buckey

Journal: Frontiers in Neuroscience

Year Published: 2021

Objective: Tests requiring central auditory processing, such as speech perception-in-noise, are simple, time efficient, and correlate with cognitive processing. These tests may be useful for tracking brain function. Doing this effectively requires information on which tests […]

Central auditory tests track cognitive function in those with HIV

Authors: Christopher Niemczak, Abigail Fellows, Jonathan Lichtenstein, Travis White-Schwoch, Albert Magohe, Jiang Gui, Jed Wilbur, Odile Clavier, Enica Massawe, Ndeserua Moshi, Micheal Boivin, Nina Kraus, Jay Buckey

Journal: JMIR Formative Research

Year Published: 2021

Background: The development of neurocognitive deficits in those infected with human immunodeficiency virus (HIV) is a significant public health problem. Previous cross-sectional studies show that performance on central auditory tests (CATs) correlates with cognitive test results […]

Correlation between computerised and standard cognitive testing in people with HIV and HIV-negative individuals

Authors: Davide De Francesco, Jonathan Underwood, Jane Anderson, Marta Boffito, Frank A Post, Memory Sachikonye, Patrick W G Mallon, Lewis Haddow, Jaime H Vera, Ken M Kunisaki, Caroline A Sabin, Alan Winston for the POPPY Study Group

Journal: AIDS Care

Year Published: 2020

We investigated the correlations and agreement between cognitive assessments made using a computerised (CogState™, six domains) and a standard pen-and-paper battery (five domains) in PWH and lifestyle-similar HIV-negative individuals. Demographically adjusted domain and global T-scores were […]

Cognitive ageing is premature among a community sample of optimally treated people living with HIV

Authors: H L Aung, M Bloch, T Vincent, D Quan, A Jayewardene, Z Liu, T M Gates, B Brew, L Mao, L A Cysique

Journal: HIV Medicine

Year Published: 2020

Objectives: Evidence of premature cognitive ageing amongst people living with HIV (PLHIV) remains controversial due to previous research limitations including underpowered studies, samples with suboptimal antiretroviral access, varying rate of virological control, high rate of AIDS, […]

Changes in functional connectivity in people with HIV switching antiretroviral therapy

Authors: Sofia Toniolo, Mara Cercignani, Borja Mora-Peris, Jonathan Underwood, Jasmini Alagaratnam, Marco Bozzali, Marta Boffito, Mark Nelson, Alan Winston, Jaime H Vera

Journal: Journal of Neuro Virology

Year Published: 2020

We assessed changes in functional connectivity by fMRI (functional magnetic resonance imaging) and cognitive measures in otherwise neurologically asymptomatic people with HIV (PWH) switching combination antiretroviral therapy (cART). In a prospective study (baseline and follow-up after […]

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