HIV-associated neurocognitive disorders

Depression, lifestyle factors and cognitive function in people living with HIV and comparable HIV-negative controls

Authors: D De Francesco, J Underwood, E Bagkeris, M Boffito, FA Post, PWG Mallon, JH Vera, I Williams, J Anderson, M Johnson, CA Sabin, A Winston, on behalf of the Pharmacokinetic and Clinical Observations in People over Fifty (POPPY) study

Journal: HIV Medicine

Year Published: 2019

Objectives: We investigated whether differences in cognitive performance between people living with HIV (PLWH) and comparable HIV-negative people were mediated or moderated by depressive symptoms and lifestyle factors. Methods: A cross-sectional study of 637 ‘older’ PLWH […]

HIV-associated neurocognitive disorders: recent advances in pathogenesis, biomarkers, and treatment

Authors: Antonia Carroll, Bruce Brew

Journal: F1000Research

Year Published: 2017

HIV-associated neurocognitive disorders (HAND) remain prevalent despite plasma viral suppression by antiretroviral agents. In fact, the prevalence of milder subtypes of cognitive impairment is increasing. Neuropsychologic testing remains the “gold standard” of diagnosis; however, this is […]

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