hippocampal volume

Performance on the Cogstate Brief Battery Is Related to Amyloid Levels and Hippocampal Volume in Very Mild Dementia

Authors: Yen Ying Lim, Victor L Villemagne, Simon M Laws, Robert H Pietrzak, David Ames, Christopher Fowler, Stephanie Rainey-Smith, Peter J Snyder, Pierrick Bourgeat, Ralph N Martins, Olivier Salvado, Christopher C Rowe, Colin L Masters, Paul Maruff, AIBL Research Group

Journal: Journal of Molecular Neuroscience

Year Published: 2016

In a group of older adults with very mild dementia, we aimed to characterize the nature and magnitude of cognitive decline as measured by the Cogstate Brief Battery, in relation to Aβ levels and hippocampal volume. […]

Hippocampal volume reduction in female but not male recent abstinent methamphetamine users

Authors: Jiang Du, Meina Quan, Wenxu Zhuang, Na Zhong, Haifeng Jiang, David N Kennedy, Amy Harrington, Douglas Ziedonis, Xiaoduo Fan, Min Zhao

Journal: Behavioural Brain Research

Year Published: 2015

Growing evidence suggests abnormalities in brain morphology including hippocampal structure in patients with methamphetamine (MA) dependence. This study was performed to examine hippocampal volume in abstinent MA users, and to further explore its relationship with cognitive […]

Relationships Between Performance on the Cogstate Brief Battery, Neurodegeneration, and Aβ Accumulation in Cognitively Normal Older Adults and Adults With MCI

Authors: Yen Ying Lim, Robert H Pietrzak, Pierrick Bourgeat, David Ames, Kathryn A Ellis, Alan Rembach, Karra Harrington, Olivier Salvado, Ralph N Martins, Peter J Snyder, Colin L Masters, Christopher C Rowe, Victor L Villemagne, Paul Maruff

Journal: Archives of Clinical Neuropsychology

Year Published: 2015

We investigated the extent to which decline in memory and working memory in beta-amyloid (Aβ) positive non-demented individuals was related to hippocampal atrophy and Aβ accumulation over 36 months. Cognitively normal older adults (CN) (n = […]

Independent Comparison of CogState Computerized Testing and a Standard Cognitive Battery With Neuroimaging

Authors: Michelle M Mielke, Stephen D Weigand, Heather J Wiste, Prashanthi Vemuri, Mary M Machulda, Davis S Knopman, Val Lowe, Rosebud O Roberts, Kejal Kantarci, Walter A Rocca, Clifford R Jack Jr, Ronald C Petersen

Journal: Alzheimer's & Dementia

Year Published: 2014

Background: Inexpensive, non-invasive tools for assessing Alzheimer-type pathophysiologies are needed. Computerized cognitive assessments are prime candidates. Methods: Cognitively normal participants, aged 51-71, with magnetic resonance imaging, fluorodeoxyglucose-positron emission tomography (FDG-PET), amyloid PET, CogState computerized cognitive assessment, […]

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