What is the optimum thiamine dose to treat or prevent Wernicke’s encephalopathy or Wernicke-Korsakoff syndrome? Results of a randomized controlled trial

Authors: Kylie M Dingwall, Jennifer F Delima, Paula Binks, Robert Batey, Stephen C Bowden

Journal: Alcoholism: Clinical and Experimental Research

Year Published: 2022

Background: The primary cause of Wernicke-Korsakoff syndrome (WKS) is thiamine deficiency, and more than 90% of cases are reported in alcohol-dependent patients. While observational studies show parenteral thiamine administration drastically reduced WKS-related mortality, relevant treatment trials […]

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