disorders

Increased Dolutegravir Peak Concentrations in People Living With Human Immunodeficiency Virus Aged 60 and Over, and Analysis of Sleep Quality and Cognition

Authors: ER Elliot, X Wang, S Singh, B Simmons, JH Vera, RF Miller, C Fitzpatrick, G Moyle, M McClure, M Boffito

Journal: Clinical Infectious Diseases

Year Published: 2019

Background: Demographic data show an increasingly aging human immunodeficiency virus (HIV) population worldwide. Recent concerns over dolutegravir-related neuropsychiatric toxicity have emerged, particularly amongst older people living with HIV (PLWH). We describe the pharmacokinetics (PK) of dolutegravir […]

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