diffusion tensor imaging

White matter correlates of slowed information processing speed in unimpaired multiple sclerosis patients with young age onset

Authors: Sindhuja Tirumalai Govindarajan, Yilin Liu, Maria Andrea Parra Corral, Lev Bangiyev, Lauren Krupp, Leigh Charvet, Tim Q Duong

Journal: Brain Imaging and Behavior

Year Published: 2020

Slowed information processing speed is among the earliest markers of cognitive impairment in multiple sclerosis (MS) and has been associated with white matter (WM) structural integrity. Localization of WM tracts associated with slowing, but not significant […]

Brief Computer-Based Information Processing Measures are Linked to White Matter Integrity in Pediatric-Onset Multiple Sclerosis

Authors: Elizabeth Bartlett, Michael Shaw, Colleen Schwarz, Charles Feinberg, Christine DeLorenzo, Lauren B. Krupp, Leigh E. Charvet

Journal: Journal of Neuroimaging

Year Published: 2019

Background and Purpose: Pediatric-onset multiple sclerosis (POMS) is a demyelinating disorder with unique clinical challenges. A brief computer-administered cognitive screening battery measuring processing speed (Cogstate) and the Brief International Cognitive Assessment in MS (BICAMS) detect cognitive […]

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