A randomized controlled trial for measuring effects on cognitive functions of adding ketamine to propofol during sedation for colonoscopy

Authors: Liang Tian, Hengfei Luan, Pin Zhu, Zhiyuan Zhang, Hongguang Bao

Journal: Medicine

Year Published: 2020

Background: The purpose of this study was to evaluate the effects of adding ketamine to propofol on cognitive functions in patients undergoing sedation for colonoscopy. Methods: In this randomized, double-blinded, and controlled study, 200 patients were […]

A randomized controlled trial of light versus deep propofol sedation for elective outpatient colonoscopy: recall, procedural conditions, and recovery

Authors: Megan Allen, Kate Leslie, Geoffrey Hebbard, Ian Jones, Tejinder Mettho, Paul Maruff

Journal: Canadian Journal of Anaesthesia

Year Published: 2015

Purpose: This study aimed to determine if the incidence of recall was equivalent between light and deep sedation for colonoscopy. Secondary analysis included complications, patient clinical recovery, and post-procedure cognitive impairment. Methods: Two hundred patients undergoing […]

Early cognitive impairment after sedation for colonoscopy: the effect of adding midazolam and/or fentanyl to propofol

Authors: Usha Padmanabhan, Kate Leslie, Audrey Singyi Eer, Paul Maruff, Brendan S Silbert

Journal: Anesthesia and Analgesia

Year Published: 2009

Background: The sedative drug combination that produces minimal cognitive impairment and optimal operating conditions during colonoscopy has not been determined. We sought to determine if the use of propofol alone results in less cognitive impairment at […]

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