Menstrual cycle characteristics across the reproductive lifespan and cognitive function in midlife women
Background: Menstrual cycle characteristics are potential indicators of hormonal exposures and may also signal cardiovascular disease risk factors, both of which are relevant to cognitive health. However, there is scarce epidemiological evidence on the association between […]
Cognitive Function in People With Pediatric Multiple Sclerosis Over 2 Years
Background and objectives: Pediatric multiple sclerosis (MS) affects children and adolescents at an important time for neurologic and cognitive development. Although cognitive impairment has been described, few longitudinal studies of cognitive functioning in pediatric MS with […]
Cogstate Brief Battery performance in assessing cognitive impairment in Taiwan: A prospective, multi-center study
Background: Early detection and accessible monitoring of dementia are crucial for timely intervention. However, traditional neuropsychological assessments are resource-intensive, and with the growing aging population, scheduling delays increased. The Cogstate Brief Battery (CBB) offers a promising, […]
Effectiveness of KarXT (xanomeline-trospium) for cognitive impairment in schizophrenia: post hoc analyses from a randomised, double-blind, placebo-controlled phase 2 study
The muscarinic receptor agonist xanomeline improved cognition in phase 2 trials in Alzheimer’s disease and schizophrenia. We present data on the effect of KarXT (xanomeline-trospium) on cognition in schizophrenia from the 5-week, randomised, double-blind, placebo-controlled EMERGENT-1 […]
Cogstate Brief Battery: Cognition and the feigning of cognitive impairment in chronic pain
Chronic pain (CP) is often associated with cognitive impairment. The Cogstate Brief Battery (CBB), a computerized assessment battery, has been studied in several neuropsychiatric disorders but not in CP. Since feigning of cognitive impairment is common […]