cognitive change

Lorazepam Challenge for Individuals at Varying Genetic Risk for Alzheimer Disease

Authors: Cynthia M Stonnington, Brian Harel, Dona E C Locke, Joseph G Hentz, Nan Zhang, Paul Maruff, Richard J Caselli

Journal: Alzheimer Disease and Associated Disorders

Year Published: 2017

Introduction: This study set out to clarify the differential acute cognitive impact of lorazepam based on varying genetic risk for Alzheimer disease. Methods: Fifty-seven cognitively unimpaired individuals aged 51 to 88, genotyped according to apolipoprotein E […]

Cognitive decline in adults with amnestic mild cognitive impairment and high amyloid-β: prodromal Alzheimer’s disease?

Authors: Yen Ying Lim, Kathryn A Ellis, Karra Harrington, Robert H Pietrzak, Joanne Gale, David Ames, Ashley I Bush, David Darby, Ralph N Martins, Colin L Masters, Christopher C Rowe, Greg Savage, Cassandra Szoeke, Victor L Villemagne, Paul Maruff

Journal: Journal of Alzheimer's Disease

Year Published: 2013

We aimed to characterize the nature and magnitude of cognitive decline in a group of adults with amnestic mild cognitive impairment (aMCI) with high and low levels of amyloid-β (Aβ) in relation to healthy older adults […]

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